Antibacterial Ingredients: Essential elements for microbial control in various personal care formulations.

Kopuron (Sodium Hyaluronate)

Effective moisturising ingredient produced by microbial fermentation

PRODUCT INFORMATION

Brand name: Kopuron Max
Chemical name: Poly(sodium-β-D-glucuronate-[1-3]-β-N-acetyl-D-glucosamine[1-4])
CAS No.: 9067-32-7
Molecular weight: 1.5 MDa
Molecular Formula: C28H44N2NaO23+

Assay:
Carbazole Assay: >91.1 – 103.5%
Identity by Infrared (IR): To match with standard
Residue on ignition: NMT 20.0%
Heavy Metals: NMT 20 ppm
pH: 6.0 – 7.0
Loss on drying: NMT 10.0%
Transparency: Min 99.5%
Protein: Max 0.1%
Glucuronic acid: 44-50%
Molecular Weight: 1.0-1.6 MDa
Viable haemolytic streptococci: Negative
Total bacteria acount: <100 cfu/g

Applications:
– Used in sunscreen products
– Used in injections to treat osteoarthritis
– Used in ear drops and artificial tears
– Used in dietary supplements
– Used as scaffolds for tissue regeneration in cosmetic surgery

Kopcinol (n-Butyl Resorcinol)

Kopcinol is used as an effective skin lightener/brightener commonly used in cosmetic preparations like creams, lotions, and gels. It can also be targeted for skin care, skin protection, and skin burn formulations. Kopcinol is an effective skin whitener/lightener, hypopigmenting agent, and tyrosinase inhibitor.

Product Information:

Brand name: Kopcinol
Chemical name: 4-n-butyl resorcinol
Molecular formula: C10H14O2
Molecular Weight: 166.22
CAS No.: 19771-63-2
Appearance: Powder form

Applications:
– Strong inhibitor of tyrosinase and peroxidase/H2O2
– Effective skin lightener and even-toner for normal skin
– Effective skin lightener for hyper-pigmented skin
– Effective against the condition of Melasma (Acquired hypermelanosis of sun-exposed areas)

Suggested formulations:
– BB Cream
– Daily cream
– Skin whitening cream
– Liquid foundation

Kopcolate (Potassium thioglycolate)

Kopcolate is an aqueous solution at the proper pH which is converted to an acid. It breaks down the disulfide bonds in Keratin and weakens the hair so that it is easily scraped off where it emerges from the hair follicle. The breakdown is affected by potassium hydroxide. They are present in excess to enable the Thioglycolic acid to react with the Cystine joining chains in hair protein.

Product Information:

Brand Name: Kopcolate
INCI Name: Potassium Thioglycolate
Chemical Name: Mercaptoacetic acid potassium salt
CAS No.: 34452-51-2
Molecular Formula: C2H3KO2S
Appearance: White to light pink liquid

Key Application: Hair removal active

Application:
– Hair removal gels
– Hair removal Cream
– Hair removal Lotion
– Hair removal foam
– Aerosol
– Roll-on

Regulatory status:
Globally approved molecule, up to 10-15%

Koplactylate (Lauryl Lactyl Lactate)

Koplactylate is a non-ionic multi-functional secondary surfactant. It is a clear, colorless liquid with a characteristic odor. It is a multifunctional secondary sulfate-free surfactant that can be easily formulated via cold mix in a surfactant system.

Product Information:

INCI name: Lauryl Lactyl Lactate
Appearance: Clear, Colorless liquid
CAS no: 910661-93-7
Water: >0.5%
Refractive Index: 1.400 – 1.5000
Solubility: Slightly soluble in water

Application:
– Skin care: Soaps, creams/lotions, facial cleansers, bubble baths, liquid soaps, cosmetic makeup
– Hair care: Shampoos, conditioners
– Body care: Body washes, bubble baths, liquid soaps
– Deodorants: Solid anhydrous antiperspirants

Properties:
– Emulsifier
– Moisturizes and softens skin
– Foam stabilizer
– Viscosity builder
– Helps solubilize active ingredients
– Multifunctional surfactant
– Very mild secondary surfactant
– Sulfate, salt, and nitrogen-free
– Improved skin feel and better hand foaming

Regulatory status:
Approved in countries like Japan, Taiwan, and USA
Not approved in countries like Europe, Australia, Canada, Philippines, and China

Koprosteine (L-(-)-2-Oxthiazolidine-4- Carboxylic acid)

Koprosteine is a modified form of cysteine which is non-toxic and more stable than cysteine. It is rapidly converted into cysteine and carbon dioxide inside the cells. Cysteine is a key component and building block of the antioxidant glutathione. Cysteine, with its thiol group, is responsible for anti-glycation of collagen and is effective against vesicants and percutaneous chemical agents. Koprosteine also has the ability to bind copper ions that are essential for tyrosinase activity, responsible for melanin inhibition.

Product Information:

Brand name: Koprosteine
Molecular Formula: C4H5NO3S
Chemical name: L-(-)-2-Oxothiazolidine-4-carboxylic acid
CAS No.: 19771-63-2
HS Code: 29341000
Appearance: White to off-white powder
Assay: 96.5% to 103.5%
Specific Rotation: -64
Solubility: Clear to lightly hazy, colorless to light yellow solution (50 mg/mL in water)

Application:
– Fighting against intrinsic skin aging
– For depigmenting or bleaching skin
– For the treatment of dry skin
– Hair growth promoter and for baldness
– In skin protective compounds effective against vesicants and percutaneous chemical agents
– Moisturizer for dry skin

Kopsova 105 (Isosorbide-2,5 dithioglycolate )

Kopsova 105 is a novel innovative hair depilatory active.

Product Information:

Brand Name: Kopsova
INCI Name: Isosorbide 2,5-dithioglycolate
Chemical Name: Isosorbide 2,5-dithioglycolate
Key Application: Hair removal novel active

Applications of Kopsova 105:
1. Fast Hair removal
2. Better moisturizing property without adding any extra moisturizer in the formulation
3. Non-irritant
4. Cosmetically elegant and pleasantly perfumed
5. Cream can be easily applied and is stable in the tube
6. Not easily discolored compared to existing depilatory actives

Kopcolate Ca (Calcium thioglycolate)

Kopcolate CA is Calcium Thioglycolate Trihydrate, which is the calcium salt of thioglycolic acid. It is an active ingredient in some hair removal products.

Product Information:

INCI Name: Calcium Thioglycolate Trihydrate
Physical form: White fine crystalline powder
Molecular Formula: C2H2CaO2S
CAS No: 65208-41-5
Chemical formula: (S-CH2-COO)2-Ca2+ X3 H2O
% Active: 99%
Molecular Weight: 184.21
pH: 11-12 (1% aqueous solution)

Application:
– Hair Depilatory – Keratolytic agent – Reducing agent

Regulatory:
Approved for OTC topical use in USA/Europe/Asia/Australia/Mexican countries.

USFDA

USFDA inspected facilities across all units

REACH

EU Region REACH-Registered Products

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