Benzethonium Chloride is a synthetic quaternary ammonium salt. It is a white crystalline solid, soluble in water. These compounds are effective in low concentrations and active against wide variety of bacteria, yeasts and fungus.
PRODUCT INFORMATION
Brand name: Kopthonium
Molecular Formula: C27H42ClNOH2
Chemical name: Benzethonium chloride
CAS No: 121-54-0
Molecular weight: 448.09
Appearance: White crystalline powder
Assay: 97-103 % on dried basis
Odour: Mild
Solubility: Soluble in water, alcohol and chloroform. Slightly soluble in ether.
Application:
Pharma As an antimicrobial preservative in injections, ophthalmic and otic preparations.
Cosmetics Deodorants, rash cream, foot odour powder, facial lotion, cleanser, make up and sun screen, mouth wash, anti-ich ointment, antibacterial moist hand wipes, antiseptic, sanitizers.
Food industry Hard surface disinfectant
Use as surfactant
Positively charged nitrogen atom of Benzethonium chloride covalently bonded to four carbon atoms
Positive charge is attracted to the skin and hair. This contributes to a soft, powdery after feel on the skin and hair as well as long lasting persistent activity against micro-organisms. Positively charged hydrophilic part of the molecule makes it cationic.
Cosmetic - Up to 0.5%. Cosmetic Ingredient review assessed this ingredient to be used safely up to 0.5% in OTC skin care products (max 0.02% concentration in eye area)
Regulatory:
Australia: Listed
EU: EINECS
USA: Listed
Canada: DSL
Japan: Listed
FDA permits BTC to be used in OTC antimicrobial drug product intended to clean skin wounds.