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Kopirox (Piroctone Olamine)

Piroctone Olamine is known for its bacteriostatic and fungistatic properties specifically working against Pityrosporumovale, which lives on the skin and is associated with dandruff and other manifestations of flaking on the face and scalp. It is often used in shampoo as a replacement of commonly used Zinc Pyrithione. It has been used over 30 years in the personal care formulations and also used as preservative and thickening agent.

Product Information

Brand Name : Kopirox

INCI Name : Piroctone Olamine

Chemical Name : 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)pyridinone,2-aminoethanol salt

CAS No : 68890-66-4

Molecular weight : 298.42

EI NECS : 272-574-2

Appearance : Powder form


1. Hair shedding and hair thinning have been reported to be affected by dandruff and seborrheic dermatitis.

2. In a comparative clinical study, it was demonstrated that Piroctone Olamine outperformed Ketoconazole and Zinc Pyrithione based shampoo in its ability to increase hair shaft diameter inn androgenic alopecia.

3. Piroctone Olamine also reduced sebum production.

4. Piroctone Olamine is the ethanolamine salt of the hydroxamic acid derivatve of piroctone.

Suggested formulations:

Transparent antidandruff shampoos.

As a preservative and thickening agent in cosmetic preparations.

In general, hair care formulations and used against seborrheic dermatitis.

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