Upcoming Exhibitions: Incosmetics Global, Barcelona Date :Tue, 6 Oct, 2020 – Thu, 8 Oct, 2020 | Patent Awarded for aqua products |
Kopcerin DO (Ethyl Hexylglycerin +Propylene Glycol +Octenidine HCL)

KOPCERIN DO (Ethyl Hexylglycerin +Propylene Glycol +Octenidine HCL)

Kopcerin  DO  is  anionic  surfactant  that  inhibits  the  growth  of  odor  causing  bacteria. Staphylococcus epidermidis  and  Bacillus  subtilis are  the  most  common  germs  that  causes  foot  odor  &  Kopcerin DO  is  more  effective  against  these  odor  causing  bacteria's, whereas  Tea  tree  oil  is  not  effective  against  these  bacteria. Trichophyton  rubrum & Trichophyton  menthagrophytes  are  the  most    common  bacteria  causing  Athletes  foot  and Kopcerin  DO  is  effective  against  these  bacteria's.

After continued exposure to antibiotics, bacteria may evolve to the point where they are no longer harmed by these compounds. Bacteria can also develop a resistance to antiseptics, but the effect is generally less pronounced. 

The mechanisms by which bacteria evolve may vary in response to different antiseptics. Low concentrations of an antiseptic may encourage growth of a bacterial strain that is resistant to the antiseptic, where a higher concentration of the antiseptic would simply kill the bacteria. In addition, use of an excessively high concentration of an antiseptic may cause tissue damage or slow the process of wound healing. Consequently, antiseptics are most effective when used at the correct concentration—a high enough concentration to kill harmful bacteria, fungi or viruses, but a low enough concentration to avoid damage to the tissue.

Octenidine is absorbed neither through the skin, nor through mucous membranes, nor via wounds and does not pass the placental barrier. However, cation-active compounds cause local irritation and are extremely poisonous when administered parenterally.

In a 2016 in vitro study of mouth rinses on gingival fibroblasts and epithelial cells octenidine showed a less cytotoxic effect, especially on epithelial cells, compared to chlorhexidine after 15 min. Wound irrigation with octenidine has caused severe complications in dogs, aseptic necrosis and chronic inflammation in penetrating hand wounds.

Prolonged contact with propylene glycol (E490) is essentially non-irritating to the skin. Undiluted propylene glycol is minimally irritating to the eye, producing slight transient conjunctivitis; the eye recovers after the exposure is removed. Exposure to mists may cause eye irritation, as well as upper respiratory tract irritation. Inhalation of propylene glycol vapors appears to present no significant hazard in ordinary applications.

octenidine has been used in Europe as an antiseptic, in concentrations of 0.1 to 2.0%. It is a substitute for chlorhexidine, with respect to its slow action and concerns about the carcinogenic impurity 4-chloroaniline. Octenidine preparations are less expensive than chlorhexidine and no resistance had been observed as of 2007.They may contain the antiseptic phenoxyethanol. It is not listed in the Annex V of authorized preservatives of the European Cosmetic Regulation 1223/2009.


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