Hyaluronic acid is a legendary star in the galaxy of cosmetics and it is almost impossible to imagine basic skin care without it. It is a natural biopolymer in the human body as an essential component in the vitreous body, ubiquitous lubricant in joints and a significant element of the extracellular matrix and the connective tissue in the skin. In terms of quantity it is the skin that contains the largest portion of it and the content decreases continuously with the advancing age.
Hyaluronic acid in cosmetic context almost exclusively relates to sodium hyaluronate.
KopuronMax sourced from the fermentation of Streptococcus equi is a high molecular weight sodium
hyaluronate with high purity, transparency and stability targeting cosmetic applications. Being non GMO in origin, KopuronMax is free of contaminants like glycosaminoglycans and animal proteins. Its unparalleled properties of moisture retention, free radical scavenging and cell proliferation maintain the skin moist and supple.
Trade name : Kopuron Max
INCI Name : Sodium Hyaluronate
Other names : Hyaluronan, Hyaluron, Hyaluronicacid
CAS No : 9067 -32-7
EINECS/ELNICS : 232-678-0
Solubility : Fully soluble in water, insoluble innon-water
The cuticular layer of human skin contains 10-20% water. As we age or skin is put to stress, its water content drops and appears dry and wrinkled. Having a high viscoelasicity, along with the capability to combine with hydrogen bonds between water molecules, hyaluronic acid of high molecular weight has great efficacy in holding water. Smearing on the skin it forms a moisturizing and ventilative membrane thus lubricating the skin as well as resisting the incursion of bacteria and dust. On the hair it also has the function of eliminating static electricity, which makes the hair easy to comb.
Hyaluronic acid clears away the reactive oxygen free radicals generated by irradiation of UV rays. It also promotes the proliferation and differentiation of the epidermal cells thus improving the regeneration of the skin. In addition, decreases the striae gravidarum and accelerate recovery of skin after birthing.
Absorbance of 1.0 aqueous solution of Kopuron Max was measured at UV 400nm and 660nm which showed anabsorbance of 99.99% substantiating its suitability incosmetic formulations.
Aqueous solution of Kopuron Max was incubated at different temperatures at different periods of time and the corresponding changes in kinematic viscosity were studied. Results prove that Kopuron Max is stable below 800C.
Kopuron Max being an extensive molecule by virtue of its high molecular weight only partially penetrates into the skin and is destined to form a film on the surface hydrating the topical layers of stratum corneum. Hydration of stratum corneum is essential for skin suppleness and elasticity, as well as for enzymatic reactions facilitating stratum corneum maturation, corneodesmolysis and desquamation. Longer the molecular chain and shorter the variation of molecular weight, the better is the formation of a polymerous net, and bigger is the surface of the skin covered by continuous moisturizing coat without disturbing overall skin gas exchange.