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Kopnol (Hexylresorcinol)

Alkylresorcinols widely occur in nature and are known to be biodegradable and present in significant amounts in the bran fractions of wheat, rye and other cereals. Works as an antiseptic, and can therefore be found in soaps, skin cleaners, and throat lozenges. Hexylresorcinol is widely used as an antihelmintic, meaning you could potentially use throat lozenges to get rid of parasitic worms if they were growing inside you. Hexylresorcinol can also be used to prevent shrimp black spot (melanosis), an unappealing surface discoloration of shrimp caused by the enzymatic production of pigmented compounds, as well as the browning and decay of fresh-cut mangoes and apples.

4-Hexyl-1,3-benzenediol; 1, 3-Dihydroxy-4-nhexylbenzene
Chemical Name : 4-Hexylresorcinol
Molecular Formula : C12H18O2
CAS # 136-77-6
EINECS/ELINCS : 205-256-4
Molecular Weight : 194.27

Physico – Chemical Properties:

Appearance Pale Yellow to white crystalline Powder
Identification To pass the test
Melting Range Between 66 °C and 68 °C
Residue on ignition NMT 0.1%
Heavy metal : Mercury NMT 3 ppm
Assay 99% (w/w) min.

Selected Safety Data:
The European Union (EU) Council of Ministers has approved hexylresorcinol as a new additive and safe to use in EU foodstuffs (June 2006; Source: Keith Nuthall)

Safety Information obtained from EUROPEAN COMMISSION, HEALTH & CONSUMER PROTECTION DIRECTORATE-GENERAL, Scientific Committee on Food SCF/CS/ADD/CONS/50 Final Opinion of the Scientific Committee on Food on 4-Hexylresorcinol (expressed on 5 March 2003) Frankos VH etal., Generally recognized as safe (GRAS) evaluation of 4-hexylresorcinol for use as a processing aid for prevention of melanosis in shrimp, Regular Toxic Pharmacol, 14(2), 202-212, 1991.

Acute Oral LD50: The oral LD50 of hexylresorcinol in the rat, rabbit, guinea pig and dog ranged from 550 to >5000 mg/kg body weight
Subacute toxicity: Oral doses up to 500 mg/kg to mice and rats showed reduced body weight only for male rats.

Packaging Sizes : 25 Kg HDPE drums
Shelf Life : Stable for 2 years from the date of manufacturing.
Storage Conditions : Store in original, sealed container, Avoid light and heat.


Literature References:
[1] Effect of different chemical compounds as coadjutants of 4-hexylresorcinol on the appearance of deepwater pink shrimp (Parapenaeus longirostris) during chilled storage; Oscar Martínez-Alvarez*, Carmen Gómez-Guillén & Pilar Montero Instituto del Frío (C.S.I.C.), José Antonio Novais 10, 28040 Madrid, Spain.
[2] Journal of Food Science: Effect of Natural Antibrowning Agents on Color and Related Enzymes in Fresh-Cut Fuji Apples as an Alternative to the Use of Ascorbic Acid"Authors: M.A. Rojas-Grau, R. Soliva-Fortuny, O. Martin-Bellosa.
[3] EC looking to cut food preservatives: prepared foods enews letter October 18, 2004.

 

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